abstract：:A possible role of tumor necrosis factor alpha (TNFalpha) in the pathomechanism of sarcoidosis must be considered in the analysis of this disorder since elevated concentrations of this cytokine have been found. In addition, TNFalpha expression could be demonstrated in sarcoid granulomata [1]. It is well known that TNF...

journal_title：Clinical rheumatology

authors： Callejas-Rubio JL,Ortego-Centeno N,Lopez-Perez L,Benticuaga MN

更新日期：2006-07-01 00:00:00

abstract：:The aim of this study is to describe the clinical features of Lebanese patients with Behçet's disease (BD) followed up at a tertiary care center in Lebanon. A retrospective review of medical records of 90 patients who fulfilled the International Study Group (ISG) criteria for diagnosis was performed. The clinical char...

journal_title：Clinical rheumatology

authors： Hamdan A,Mansour W,Uthman I,Masri AF,Nasr F,Arayssi T

更新日期：2006-05-01 00:00:00

abstract：:Although the Health Assessment Questionnaire (HAQ) and the Modified Health Assessment Questionnaire are useful tools for assessing and monitoring patients with rheumatic diseases, they have a "floor effect" and do not fully reflect the psychological status of patients. Recently, the Multidimensional Health Assessment ...

journal_title：Clinical rheumatology

authors： Lee SS,Park MJ,Yoon HJ,Park YW,Park IH,Park KS

更新日期：2006-05-01 00:00:00

abstract：:A 63-year-old man with hypertrophic pachymeningitis (HP) and an undifferentiated connective tissue disease is described. Combined therapy with prednisolone and azathioprine improved his symptoms. The association between an undifferentiated connective tissue disease and HP is discussed. ...

journal_title：Clinical rheumatology

authors： Lampropoulos CE,Zain M,Jan W,Nader-Sepahi A,Sabin IH,D' Cruz DP

更新日期：2006-05-01 00:00:00

abstract：:Catastrophic anti-phospholipid syndrome (CAPS) is a medical emergency characterized by thromboses of multiple small vessels of internal organs and the brain. Herein we present a patient with primary anti-phospholipid syndrome who developed CAPS manifested by hepatic, renal and splenic artery thromboses, as well as cer...

journal_title：Clinical rheumatology

authors： Zeller L,Almog Y,Tomer A,Sukenik S,Abu-Shakra M

更新日期：2006-05-01 00:00:00

abstract：:The aim of this study was to determine the emotional and sociodemographic characteristics of patients with ankylosing spondylitis (AS) and to investigate the impact of the disease on their social life and quality of life (QOL). This study included 101 patients with the diagnosis of AS. All patients filled in a questio...

journal_title：Clinical rheumatology

authors： Ozgül A,Peker F,Taskaynatan MA,Tan AK,Dinçer K,Kalyon TA

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:We aimed to evaluate the effect on renal functions and blood pressure of the addition of low dose aspirin (LDA) to cyclooxygenase-2 (COX-2) inhibitors or nonselective NSAIDs. METHODS:Two groups each containing 14 patients with one group using celecoxib and the other indomethacin regularly for at least 1 week...

journal_title：Clinical rheumatology

authors： Pamuk ON,Cakir N

更新日期：2006-02-01 00:00:00

abstract：:Scleredema (also called scleredema of Buschke) is a fibromucinous connective tissue disorder of unknown cause that belongs to a group of scleroderma-like disorders. We report the case of a 64-year-old lady with long-standing scleredema, associated with a paraprotein, and progressing to multiple myeloma and AL amyloido...

journal_title：Clinical rheumatology

authors： Dziadzio M,Anastassiades CP,Hawkins PN,Potter M,Gabrielli A,Brough GM,Black CM,Denton CP

更新日期：2006-02-01 00:00:00

abstract：:The objective of this study was to determine the appropriate volume of saline to obtain a beneficial effect of arthroscopic lavage and the prognostic factors related to the clinical effect in a refractory rheumatoid knee. Arthroscopic lavage or arthrocentesis was performed in a random manner in 142 patients with relap...

journal_title：Clinical rheumatology

authors： Tanaka N,Sakahashi H,Hirose K,Ishima T,Ishii S

更新日期：2006-02-01 00:00:00

abstract：:Pain is a leading cause of morbidity worldwide, with published data showing its prevalence as high as 50% for chronic pain in the European population. This prevalence is likely to continue to rise, particularly in elderly people with comorbid conditions and complex aetiologies of pain. There is thus a rapidly growing ...

journal_title：Clinical rheumatology

authors： Langford RM

更新日期：2006-01-01 00:00:00

abstract：:We report a patient with idiopathic portal hypertension (IPH) associated with systemic sclerosis (SSc) and Sjögren's syndrome. A 72-year-old Japanese woman was admitted to our hospital because of Raynaud's phenomenon, sclerodactyly, and dyspnea. The patient had splenomegaly, esophageal varices in the absence of extrah...

journal_title：Clinical rheumatology

authors： Kogawa H,Migita K,Ito M,Takii Y,Daikoku M,Nakao M,Miyashita T,Kimura H,Ezaki H,Nakamura M,Yatsuhashi H,Eguchi K,Ishibashi H

更新日期：2005-09-01 00:00:00

abstract：:The objective of this study was to determine possible differences in the outcome of patients with rheumatoid arthritis (RA) with disease onset early and late in life. As part of a broader outcome study of RA which included patients seen in the division of Rheumatology of Hospital Universitario Marqués de Valdecilla of...

journal_title：Clinical rheumatology

authors： Calvo-Alén J,Corrales A,Sánchez-Andrada S,Fernández-Echevarría MA,Peña JL,Rodríguez-Valverde V

更新日期：2005-09-01 00:00:00

abstract：:A white female patient developed overlapping features of systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) with severe pulmonary compromise. She was treated with steroids and azathioprine, which improved her clinical condition and spirometric status. In May 2002 she presented with continuous pain in her ...

journal_title：Clinical rheumatology

authors： Cavallasca JA,Laborde HA,Araujo MB,Nasswetter GG

更新日期：2005-08-01 00:00:00

abstract：:A 61-year-old female with a history of vaginal dryness, Raynaud's phenomenon, xerostomia and xerophthalmia presented with exertional dyspnoea and weakness. Laboratory and instrumental examinations enabled us to make the diagnosis of primary Sjögren's syndrome, while cardiologic and imaging investigations evidenced iso...

journal_title：Clinical rheumatology

authors： Bertoni M,Niccoli L,Porciello G,Storri L,Nannini C,Manes A,Palazzini M,Galiè N,Cantini F

更新日期：2005-08-01 00:00:00

abstract：:We report the case of a 57-year-old woman presenting with persistent cough, weight loss, and fever. An extensive work-up revealed laboratory signs of inflammation and a mild thickening of the aortic wall on computed tomographic scan of the thorax. These findings raised the suspicion of large vessel vasculitis that was...

journal_title：Clinical rheumatology

authors： Van der Schueren B,Lambert M

更新日期：2005-08-01 00:00:00

abstract：:Upper lobe fibrobullous disease is a well-known finding in advanced stages of ankylosing spondylitis (AS). In this report, we present a 57-year-old male patient who was diagnosed with a right apical cavitary lesion after coming to us with the complaint of haemoptysis. The patient underwent upper lobe segmentectomy and...

journal_title：Clinical rheumatology

authors： Pamuk ON,Harmandar O,Tosun B,Yörük Y,Cakir N

更新日期：2005-08-01 00:00:00

abstract：:The objective of this study was to determine tendon involvements and enthesal abnormalities in patients with rheumatoid arthritis (RA) using high-resolution ultrasonographic images and to compare the findings with those seen in patients with ankylosing spondylitis (AS) and healthy controls. A total of 24 patients with...

journal_title：Clinical rheumatology

authors： Genc H,Cakit BD,Tuncbilek I,Erdem HR

更新日期：2005-06-01 00:00:00

abstract：:Hepatitis C-associated osteosclerosis (HCAO) is an impressive example of acquired diffuse osteosclerosis in adults, recently described in ten patients infected with hepatitis C virus (HCV). Its hallmark is a painful and generalized increase of bone mass. Bone biopsies show enhanced accretion rate, usually without hist...

journal_title：Clinical rheumatology

authors： Manganelli P,Giuliani N,Fietta P,Mancini C,Lazzaretti M,Pollini A,Quaini F,Pedrazzoni M

更新日期：2005-06-01 00:00:00

abstract：:Hyperimmunoglobulinemia D syndrome (HIDS) is newly recognized and resembles familial Mediterranean fever (FMF). It is inherited as an autosomal recessive trait. Mutation of the gene coding for mevalonate kinase is responsible for the disease. The gene is located at chromosome 12q24. The patients initially described we...

journal_title：Clinical rheumatology

authors： Hammoudeh M

更新日期：2005-02-01 00:00:00

abstract：:Familial Mediterranean fever (FMF) is prevalent among Arabic, Turkish, Armenian, and Jewish people and it must always be considered in the differential diagnosis of patients from these ethnic groups presenting with recurrent abdominal pain with fever. In cases of fever and recurrent abdominal pain, acute pancreatitis ...

journal_title：Clinical rheumatology

authors： Birlik M,Demir T,Zeybel M,Akar S,Onen F,Comlekci A,Tunca M,Akkoc N

更新日期：2004-12-01 00:00:00

abstract：:Monovariate and multivariate analyses including logistic regression were performed to determine associations among predicting variables [age, gender, immunofluorescence pattern, and anti-nuclear antibody (ANA) titer] and anti-extractable nuclear antigen (ENA) and -dsDNA antibodies (Abs) in 1089 patients with positive ...

journal_title：Clinical rheumatology

authors： Kang I,Siperstein R,Quan T,Breitenstein ML

更新日期：2004-12-01 00:00:00

abstract：:Subcutaneous rheumatoid nodules occur commonly in advanced cases of rheumatoid arthritis and are the most common extra-articular lesion of this disease. We present a case of a very unusual giant rheumatoid nodule that developed on the lateral side of a knee. The case was devoid of systemic symptoms of arthritis and th...

journal_title：Clinical rheumatology

authors： Mine T,Tanaka H,Taguchi T,Ihara K,Ishida Y,Sugitani T,Kawai S

更新日期：2004-10-01 00:00:00

abstract：:The pathogenesis of the idiopathic inflammatory myopathies has been postulated to be an environmental trigger causing the expression of the disease in a genetically predisposed patient. We report a case of anti-Jo1 antibody-positive myositis which was associated with pleural effusions, pericardial effusion with tampon...

journal_title：Clinical rheumatology

authors： Derk CT,Sandorfi N,Curtis MT

更新日期：2004-08-01 00:00:00

abstract：:The aim of this study was to evaluate the safety and efficacy of azathioprine in the treatment of interstitial lung disease (ILD) associated with systemic sclerosis (SSc). The records of patients with SSc with ILD who were treated with azathioprine were reviewed. Patients were treated with azathioprine and low-dose pr...

journal_title：Clinical rheumatology

authors： Dheda K,Lalloo UG,Cassim B,Mody GM

更新日期：2004-08-01 00:00:00

abstract：:We describe the case of a patient with anticentriole antibody-positive scleroderma spectrum disorder (SSD) who developed pulmonary hypertension. A 54-year-old woman had noticed Raynaud's phenomenon and digital ulcers during the winter for the past 10 years. Although sclerodactyly was not present, digital ulcers, swell...

journal_title：Clinical rheumatology

authors： Hayakawa I,Sato S,Hasegawa M,Echigo T,Takehara K

更新日期：2004-06-01 00:00:00

abstract：:The aim of this study was to determine the serum interleukin-18 (IL-18) levels in patients with systemic lupus erythematosus (SLE) and to assess their relationship with disease activity. Thirty-five patients with SLE and 35 age- and sex-matched controls were enrolled in this study. Paired serum samples were collected ...

journal_title：Clinical rheumatology

authors： Park MC,Park YB,Lee SK

更新日期：2004-06-01 00:00:00

abstract：:The aim of this study was to evaluate whether corticosteroid use is the etiological agent in acute pancreatitis in patients with systemic lupus erythematosus, or whether it is related to the underlying connective tissue disorder. Hospital admissions at Thomas Jefferson University Hospital between 1982 and 2002 that ca...

journal_title：Clinical rheumatology

authors： Derk CT,DeHoratius RJ

更新日期：2004-04-01 00:00:00

abstract：:We report a case of cytomegalovirus (CMV) enteritis in a 31 year-old -woman with lupus enteritis. In August 2002 the patient complained of severe abdominal pain. An abdominopelvic CT scan at the time showed free air in the peritoneal cavity and wall thickening of the ileal loop. She was diagnosed as having panperitoni...

journal_title：Clinical rheumatology

authors： Bang S,Park YB,Kang BS,Park MC,Hwang MH,Kim HK,Lee SK

更新日期：2004-02-01 00:00:00

abstract：:The aim of this study was to investigate the association between the polymorphism of transporters associated with antigen processing ( TAP1/TAP2) genes and rheumatoid arthritis in Chinese patients. A total of 100 RA patients and 99 healthy control subjects were enrolled. Analyses with polymerase chain reaction (PCR) b...

journal_title：Clinical rheumatology

authors： Yu MC,Huang CM,Wu MC,Wu JY,Tsai FJ

更新日期：2004-02-01 00:00:00

abstract：:Erdheim-Chester disease (ECD) is a disseminated non-Langerhans' cell histiocytosis with multisystem involvement, including characteristic sclerotic musculoskeletal lesions. We present the case of a 27-year-old woman with a fulminant course and atypical involvement by ECD manifesting as extensive cerebrovascular diseas...

journal_title：Clinical rheumatology

authors： Lyders EM,Kaushik S,Perez-Berenguer J,Henry DA

更新日期：2003-12-01 00:00:00

abstract：:The aim of this study was to investigate generalized osteoarthritis (GOA) by combining X-ray grading of the knee, spine and hand using biochemical markers for arthritis, such as YKL-40 and urinary pyridinoline (Pyr). One hundred and thirty postmenopausal women with primary knee osteoarthritis (OA) aged 55-92 years wer...

journal_title：Clinical rheumatology

authors： Abe M,Takahashi M,Naitou K,Ohmura K,Nagano A

更新日期：2003-12-01 00:00:00

abstract：:Rheumatic diseases do not usually cluster in time and space. It has been proposed that environmental exposures may initiate autoimmune responses. We describe a cluster of rheumatic diseases among a group of health center employees who began to complain of symptoms typically related to moldy houses, including mucocutan...

journal_title：Clinical rheumatology

authors： Luosujärvi RA,Husman TM,Seuri M,Pietikäinen MA,Pollari P,Pelkonen J,Hujakka HT,Kaipiainen-Seppänen OA,Aho K

更新日期：2003-12-01 00:00:00

abstract：:A prospective, randomised, double-blind study was carried out to compare the respective efficacies of transforaminal and interspinous epidural corticosteroid injections in discal radiculalgia. Thirty-one patients (18 females, 13 males) with discal radicular pain of less than 3 months' duration were consecutively rando...

journal_title：Clinical rheumatology

authors： Thomas E,Cyteval C,Abiad L,Picot MC,Taourel P,Blotman F

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVES:To establish the prevalence of the associated secondary diseases in patients with Raynaud's phenomenon (RP) attending a rheumatology specialty centre and to determine the frequency with which a secondary illness develops in those having RP, in absence of a well-defined secondary cause. METHODS:118 consecuti...

journal_title：Clinical rheumatology

authors： De Angelis R,Del Medico P,Blasetti P,Cervini C

更新日期：2003-10-01 00:00:00

abstract：:Although peripheral blood eosinophilia is observed in patients with active inflammatory rheumatoid arthritis (RA), RA is not a recognised cause of pulmonary eosinophilia. We describe a 55-year-old woman affected by chronic eosinophilic pneumonia (CEP) concomitantly with an initiation of RA. Both diseases responded rap...

journal_title：Clinical rheumatology

authors： Kwak JJ,Chang JE,Lee J,Cho YJ,Sung SH

更新日期：2003-09-01 00:00:00

abstract：:The aim of this study was to analyse microvascular damage and compensatory angiogenesis in skin from patients with systemic sclerosis (SSc) compared with systemic lupus erythematosus (SLE), Raynaud's phenomenon (RP) and healthy controls. Immunohistochemistry was used for skin biopsies (9 SSc, 10 SLE, 9 RP and 12 healt...

journal_title：Clinical rheumatology

authors： Konttinen YT,Mackiewicz Z,Ruuttila P,Ceponis A,Sukura A,Povilenaite D,Hukkanen M,Virtanen I

更新日期：2003-09-01 00:00:00

abstract：:Although mesenteric vasculitis due to Henoch-Schönlein purpura (HSP) is relatively uncommon, it is the most life-threatening manifestation associated with high mortality. We describe a 15-year-old boy with HSP who had massive gastrointestinal bleeding and ileus but delayed onset of the purpuric rash. Abdominal ultraso...

journal_title：Clinical rheumatology

authors： Wang L,Huang FC,Ko SF,Cheng MT

更新日期：2003-05-01 00:00:00

abstract：:In this study we aimed to investigate the findings in patients with adult-onset Still's disease (AOSD) admitted with fever of unknown origin (FUO) during the last 18 years in our unit, in order to discover the ratio of such patients to all patients with FUO during the same period, and to determine the clinical feature...

journal_title：Clinical rheumatology

authors： Mert A,Ozaras R,Tabak F,Bilir M,Ozturk R,Ozdogan H,Aktuglu Y

更新日期：2003-05-01 00:00:00

abstract：:We report a young male with recent onset of rheumatoid arthritis (RA) in whom the remarkable severity of the disease led to additional investigations. The only significant finding was mediastinal lymphadenopathy, without lung involvement. Biopsy of the mediastinal lymph node revealed pathological findings typical of s...

journal_title：Clinical rheumatology

authors： Markovits D,Schapira D,Wiener A,Nahir AM

更新日期：2003-02-01 00:00:00

abstract：:Wegener's granulomatosis (WG) is a systemic granulomatous vasculitis that typically affects the upper airways, lungs and kidneys. Lymphadenopathy is rare in patients with WG. Here, we present the first case of WG whose initial manifestation was superficial lymphadenopathy (i.e. supraclavicular and axillary lymphadenop...

journal_title：Clinical rheumatology

authors： Hashizume T,Yamaguchi T,Matsushita K

更新日期：2002-11-01 00:00:00